U.S. Supreme Court Carpenter v. United States decision to public savfety and privacy issues.
Discuss the following and including speaker notes:
What is the case history and background?
What is the legal outcome and decision of the court?
What are the implications of the legal outcome on public safety and privacy?
amples which had higher parasite density per microliter of blood and vice versa Molecular markers of drug resistance Pfdhfr: To monitor the PYR drug resistance in collected 295 samples, out of these samples, 288 samples could be amplified for dhfr and dhps both gene. In dhfr gene, double mutation was observed highest frequency (71.9%) followed by single (9%) and triples (2.4%) mutation and 16.7% samples had wild type genotype. Frequency of double mutation (59+108) was higher in Madhya Pradesh (97.5%) followed by Chhattisgarh (75.4%), Jharkhand (64.8%) and Odisha (46.5%) of the samples. Single mutation was seen 18.3%, 12.7%, 3% and 2.5% in Odisha, Jharkhand, Chhattisgarh and Madhya Pradesh samples, respectively. Triple mutation was observed in 9.1% isolate in Chhattisgarh and only 1.4% isolates from Jharkhand. While wild genotype was observed in highest frequency (35.2%) in Odisha followed by Jharkhand (21.1%) and Chhattisgarh isolates (12.1%). Pfdhps:- To monitor the SDX drug resistance pattern in amplified of 288 samples, wild type dhps genotype was prevalent with highest frequency (51%) followed by dhps triple (26%), double (11.8%), & single (11.1%) mutation. Frequency of wild type genotype was higher in Odisha (76.1%), followed by Chhattisgarh (74.2%), Madhya Pradesh (31.3%) and Jharkhand (26.8%). Triple mutation (436+437+540) in dhps gene was observed with frequency of 52.1%, 31.3%, 16.9% and 1.5% in the isolates collected from Jharkhand, Madhya Pradesh, Odisha and Chhattisgarh, respectively. However, double mutation was highly prevalent in Madhya Pradesh i.e. 30.0% as compared to the frequency of 7.6%, 4.2% and 2.8%in Chhattisgarh, Odisha and Jharkhand of isolates, respectively. Single mutation in pfdhps was found in the18.3%, 16.7%, 7.5% and 2.8%of the samples from Jharkhand, Chhattisgarh Madhya Pradesh and Odisha, respectively. Mutation pattern in dhps gene in relation with residual SDX: Mutation was analyzed in dhps gene in two groups; residual levels SDX (+ve) (n=45) and SDX (-ve) (n=235) on day 0. Mutation rate in dhps gene was higher in those patients had residual SDX (57.8%) as compared to without residual SDX (48.5%) concentration on day on day 0. Triple mutation in dhps was also higher (33.3%) in SDX (+) as compared to SDX (-) patients on day 0. Mutation in codo>GET ANSWER