• What is the drug
• What is the disease(s) that it treats?
• If the drug is now used to treat multiple diseases, highlight the one(s) that was first focused on in the target identification studies which drove the subsequent discovery of a lead compound and drug development.
• How is the drug used?
• How effective / successful is the drug?
• Historical details of when the drug was first approved, its current status.
• What is the therapeutic pharmacological target(s) that this drug binds to?
• How was this target identified as being promising for the treatment of the disease?
• What is the therapeutic pharmacological target(s) that this drug loinds to?
• How was this target identified as being promising for the treatment of the disease?
• What are the key findings which established the endogenous role of this pharmacological target, and how do these link with the disease?