1. In older adults with COPD, how does continual smoking as compared to those who stopped smoking affect the progression of their disease in 5 years?
2. In patients with sleep apnea, secondary to COPO, how much effective is high flow nasal cannula than CPAP machine in sleeping pattern for the next 1 year?
3. In patients with COPO, how effective is albuterol than solumedrol in improving pulmonary function for the next 5 years?
