Discuss the influence of globalization, social responsibility and environmental sustainability on strategic management of a corporation.
information of immediate exposure to toxicants and their enduring health effects to human health through model organisms. BPA is dangerous because when exposed to extreme environments (i.e. Heat, acidic or basic), the ester bond links in BPA go through hydrolysis which enables a monomer to be released.3 BPA has structural and functional resemblance to estrogen (Fig. 1), specifically 17 beta estradiol (E2) as well as, alpha and beta estrogen receptors.7 Due to the resemblance, it has shown to affect the reproductive system in both sexes disrupting gene expression in embryos as well as endocrine pathways, semen quality, and fecundity/infertility. Effects of BPA’s presence can be seen through low dose exposure, when there is high exposure the reactions are inhibited therefore no response is seen.3 Due to the increase in exposure we have of BPA, there has been in infertility. Many studies have been trying to prove what exactly does our environment have to deal with fecundity. Exposure to BPA is so common that it is impossible to not be affected by it. Mice, sea urchin, nematodes, zebrafish, and even humans have had numerous case-studies done to observe the way the exposure affects them as well as what is the relation between BPA and infertility. Due to all the speculation of BPA and its effect on human health many questions came about. Different types of exposures such as in early stages of life, low doses, long term, and the exposure to several different toxicants and their effects were all questioned. These experiments have all of these questions in common along with one goal in mind. What exactly is the effect that BPA has on human health? One question that is most intriguing is, what is happening at a cellular level? Sometimes we are able to see the results of situations at a cellular level meanwhile others may not be as conspicuous so they are less likely to be indicated. BPA has effected humans at a cellular level which is shown in this specific experiment with fish. Inherited chromosomes (maternal or paternal) express imprinted genes in at least one non- sex cell or extraembryonic organ (outside the embryo). Normal utero development needs the correct allele-specific expression (DNA methylation and chromatin composition) of imprinted genes in the embryo and placenta. A single hit to genes by an endocrine disruptor results in critical after-effects in health and development due to the fact that imprinted genes are functionally haploid. Marine life is affected by BPA exposure as much as we are, due to the fact that our wastes ends up in the ocean causing the exposure to BPA on aquatic life.>GET ANSWER