Respond to any 2 of the following:
- Describe the powers and functions of the three branches of government.
- Describe how James Madison in Federalist 10 outlines a plan to limit popular government and the “violence of faction.” Is Madison’s plan still working today? Why or why not?
- Describe the tension between the Tenth Amendment and the necessary and proper clause of the U.S. Constitution. Give an example to illustrate this tension.
- Explain why and how the power of the U.S. federal government has expanded over time while the power of states has, generally speaking, been on the decline.
is the relation between BPA and infertility. Due to all the speculation of BPA and its effect on human health many questions came about. Different types of exposures such as in early stages of life, low doses, long term, and the exposure to several different toxicants and their effects were all questioned. These experiments have all of these questions in common along with one goal in mind. What exactly is the effect that BPA has on human health? One question that is most intriguing is, what is happening at a cellular level? Sometimes we are able to see the results of situations at a cellular level meanwhile others may not be as conspicuous so they are less likely to be indicated. BPA has effected humans at a cellular level which is shown in this specific experiment with fish. Inherited chromosomes (maternal or paternal) express imprinted genes in at least one non- sex cell or extraembryonic organ (outside the embryo). Normal utero development needs the correct allele-specific expression (DNA methylation and chromatin composition) of imprinted genes in the embryo and placenta. A single hit to genes by an endocrine disruptor results in critical after-effects in health and development due to the fact that imprinted genes are functionally haploid. Marine life is affected by BPA exposure as much as we are, due to the fact that our wastes ends up in the ocean causing the exposure to BPA on aquatic life. Rainbow Trout (Oncorhynchus mykiss) is an ecologically and economically important species due to commercial and predator purposes. Rainbow trout showed how BPA exposure to rainbow trout eggs caused molecular reprogramming of the liver in two generations. Abnormal development, reproductive failure and disrupted metabolism are induced by chronic early and regular development exposure to BPA.12 Long term developmental issues are due to the fact that BPA is maternally transferred in fish12. In one experiment, the hypothesis BPA accumulation in rainbow trout eggs precedes effects that are long-term to be carried into following generations. Growth and changes of more than two generations were monitored from BPA containing eggs (specifically in liver transcriptome, using RNA-sequencing).12In result the eggs growth is impacted at certain stages due to BPA exposure in eggs (Fig.4). Although there was a reduction in growth, later on in their lifespan there was a catch-up period for them. This period allowed the trout to catch up on the growth scale which proved to be the BPA disrupting some sort of developmental programming. The results also proved that the second generation were BPA free(still raised from BPA-treated eggs) however, in the beginning stages of life and period of growth showed reduced growth and lipid buildup in the liver in older individuals (Fig. 3). The lowest BPA concentration which represents our environmental exposure proved to be the most harmful, which affected oocyte growth and maturation. As well as affecting the signals that deal with the last phase of oogenesis.12 The higher >GET ANSWER