A comprehensive case study report describes clinical case in order to provide new insights on a process, phenomenon, or observation within the biomedical setting. As such, case study reports are not merely descriptions of a patient’s clinical features, diagnoses, needed treatments and prognosis. Instead, a case report should have a well-defined thesis statement, in which the case itself serves as strong evidence supporting for the thesis statement.

Review the following case study describing a patient with a number of frequently observed comorbidities. For this assignment, you will evaluate the various clinical characteristics of this patient. In addition, you will review the literature – as you have done for previous assignments – and explain how these clinical characteristics relate to the pathophysiology of the observed comorbidities. In order to do this, you have been provided with a series of prompts to discuss in your evaluation. Make sure that you are integrating these into a single narrative, and are not separating your responses by question number. As part of this, you should include an introduction with a well-defined thesis statement, transition sentences that connect the different ideas, and a conclusion. Submit your answers using APA format, well-written sentences, and detailed explanations. Your analysis must be scientifically sound, necessary, and sufficient. Paper must be a minimum of 6 pages, plus references and title page.

You must also include a bibliography of at least 3 sources (with at least one non-Internet source). Your textbook may not be included as a source for this assignment. Refer to the rubric for more information on how your assignment will be graded.

Case Study

M.K. is a 45-year-old female, measuring 5’5” and weighs 225 lbs. M.K. has a history of smoking about 22 years along with a poor diet. She has a history of Type II diabetes mellitus along with primary hypertension. M.K. has recently been diagnosed with chronic bronchitis. Her current symptoms include chronic cough, more severe in the mornings with sputum, light-headedness, distended neck veins, excessive peripheral edema, and increase urination at night. Her current medications include Lotensin and Lasix for the hypertension along with Glucophage for the Type II diabetes mellitus.

The following are lab findings that are pertinent to this case:
patients vitals:
bp 158/98
CBC
hematocrit 57%
glycosylated hemoglobin (HgA1c) 7.3%
ARTERIAL BLOOD GAS ASSESSMENT
PaCO2 52mm Hg
PaO2 48mm Hg
LIPID PANEL
cholesterol 242 mg/dl
HDL 32 mg/dL
LDL 173 mg/dL
Tryglycerides 1000 mg/dL

As you develop your case study, be certain to address the following issues as they relate to common comorbidities observed in patients.

Describe the clinical findings that correlate with M.K.’s chronic bronchitis. Based on current literature, review the types of treatment and recommendations that would be appropriate for M.K.’s chronic bronchitis?
Describe the type of heart failure would you suspect with M.K. Based on current literature, review the pathogenesis of how this type of heart failure develops.
According to the American Heart Association 2017 new guidelines, and M.K.’s B.P. value, describe the stage of hypertension is she experiencing. Based on current literature, review the rationale for her current medications for her hypertension. Also, discuss the impact of this disease in the U.S. population.
According to the lipid panel, what other condition is M.K. at risk for? Based on current literature, review what other medications should be given and explain why. What additional findings in the patient correlate with both hypertension and Type II diabetes mellitus.
Based on current literature, review the significant of the lab value for HbA1c. Explain how this value relates to normal/abnormal body function in the patient.

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