A. You have been given the task of setting up a molecular diagnostics laboratory to provide pharmacogentic testing. What factors would you influence the scale and repertoire of tests you offer and give two specific example of genetic tests that are used to determine drug therapy?
B. Describe how fluorescence in situ hybridisation (FISH) is used in cancer diagnosis and prognosis.
C. Molecular techniques are being used increasingly in the diagnosis. Briefly describe how DNA technology is changing the practice of the disorder’s diagnosis.
D. Screening for genetic diseases has been influenced by DNA-based molecular techniques. Give two unrelated examples of how the use of molecular diagnostic has facilitated screening and how this has made a difference.
My school is a Local Authority (LA) maintained school nestled in outer London, a suburb located on the boundary of East London and Essex consisting of a large Asian community, the largest groups in the school being of Bangladeshi, Pakistani and Indian Heritage, based in an affluent area where unemployment level is low, playing a pivotal part in the schools performance: “Compare school and college performance” (Gov.UK, 2016) KS2 achievement Dec 2015: Level 4 or above; reading, writing and math’s I believe poverty; unemployment and borough deprivation has an impact on a child’s development, where parents are less engaged with their children’s education and progression, in contrast to those parents who are employed. My school promotes community cohesion successfully and understands the responsibility in equipping pupils to thrive and live with people from many different backgrounds. 1.2 Key characteristics and type of school: My school is a mixed primary formed in 2006 amalgamating with an Infant School. Age range is 4 to 11 years with a nursery setting. Ofsted rated ‘Outstanding’ in 2013 (Ofsted, 2013). Recently becoming 4-form entry in Reception and Year 1 consisting over 700 pupils. My school has extensive grounds with a large field and 2 playgrounds. A new building extension was completed in September 2016 giving a total of 23 teaching classes; much-needed library, extra dining space along with 2 halls for sports and assemblies, all classrooms are well resourced with high quality ICT, also benefiting with a swimming pool based in the garden area. Currently, there is a below average proportion of pupils supported by additional funding through the pupil premium, including those to be eligible for free school meals also a lower than average proportion of pupils with a statement of special educational needs. 1.3 Organisation of Business Management and Professional roles within: As per above organogram, we currently do not have a SBM so the leadership team share duties associated with this role. The Deputy Head, Office and Site Managers report to the Associate Head who reports to the Executive Head. The Office and Site Mangers carry out most of procurement, financial and facilities management tasks. The Associate and Deputy Head manage HR and Marketing whilst overseeing the school budget. There is a strong need for a SBM in our school so he/she can manage the additional responsibilities the heads and deputy have undertaken, to ensure their time is dedicated to high standard of teaching and learning, not dealing with certain staff issues or the day-to-day budget, this will also enable more productivity from all resources through better management, a SBM would play an important strategic role in implementing best value by making the most of school resources in the most sustainable and environmentally friendly manner, so more is available for the school’s core activities.>GET ANSWER