Acute Lymphoblastic Leukemia (ALL)
Scenario 1: Acute Lymphoblastic Leukemia (ALL)
An 11-year-old boy is brought to the clinic by his parents who states that the boy has not been eating and listless. The mother also notes that he has been easily bruising without trauma as he says he is too tired to go out and play. He says his bones hurt sometimes. Mother states the child has had intermittent fevers that respond to acetaminophen.
Maternal history negative for pre intra, or post-partum problems
MH: Negative. Easily reached developmental milestones
PE: reveals a thin, very pale child who has bruises on his arms and legs in no particular pattern
LABS: CBC revealed Hemoglobin of 6.9/dl, hematocrit of 19% and platelet count of 80 000/mm3 The CMP demonstrated a blood urea nitrogen (BUN) of 34m
g/di and creatinine of 2 9 mg/dl.
DIAGNOSIS: acute leukemia and renal failure and immediately refers the patient to the Emergency Room where a pediatric hematologist has been consulted
and is waiting for the boy and his parents.
CONFIRMED DX: acute lymphoblastic leukemia (ALL) was made after extensive testing.
Question
Explain what ALL is?