Autoimmune Diseases

  1. Explain the pathophysiology of an autoimmune disease in relation to destruction of the synovial joints, capsule, and membrane to Rheumatoid arthritis. 2. Compare and contrast signs and symptoms of OA ( osteoarthritis) to RA (Rheumatoid arthritis). 3. Describe the difference between Heberden's nodes vs Bouchards nodes. 4. What is Gouty arthritis and how does it differ from OA ( osteoarthritis).  
In comparison to osteoarthritis (OA), RA is usually more aggressive resulting in swelling around joints accompanied by reddened skin tightness sensation upon movement potentially other symptoms such fever fatigue etc.. OA on contrary tends begin later life often initially presenting itself milder manner without too much inflammation involved although can still cause great deal pain nonetheless depending how far condition progresses during progression rate differs greatly between individuals one factor being age since younger people tend suffer faster deterioration than older ones who may experience slower advances within same timeframe however both equally debilitating none less disheartening. Heberden's nodes are bony swellings found along distal interphalangeal joints whereas Bouchard's nodes refer enlarged knuckles located proximal area same hand/wrist which often occur conjunction each other particularly those suffering from OA conversely situation when talking about Gouty Arthritis different altogether given fact it caused buildup uric acid crystals particular joint triggering sudden intense flare-ups pain tenderness redness swelling area(s) affected directly while also inflame nearby areas unlike OA associated cases where minor forms deformity visible due wear tear overtime thanks reading!

Sample Solution

Rheumatoid arthritis (RA) is an autoimmune disorder characterized by the destruction of synovial joints, capsule, and membrane due to inflammation and eventual joint destruction. As a result of this destruction, the body’s immune system mistakenly attacks healthy tissues in the affected areas causing pain, swelling, stiffness and limited mobility. This process begins with tissue breakdown as cells within these areas become impaired leading to influxes chemicals like cytokines; these substances then trigger further responses from other cell types involving increased production antibodies that damage surrounding structures eventually deforming them over time as well.