Discuss the characteristics or attributes that should be appraised when evaluating qualitative and quantitative designs in relation to rigor or quality of its type? How do the characteristics or attributes of greatest importance in qualitative or quantitative type differ? Give an example.
The control group received Standard EnteraMeal (Karen Pharma and Food supplement Co., Iran) for 14 days, and the taurine group received daily amount of 30mg/kg with a maximum dose of 3 grams/day of taurine powder (Nutricost, USA) for 14 days in addition to the Standard EnteraMeal (Karen Pharma and Food supplement Co., Iran). Taurine powder was given to patients in two divided doses. Weight of the Patients was measured from the entrance by the scale of hospital bed. Patients’ height was calculated by measuring the knee height and then, by the formula. Body Mass Index (BMI) was calculated by dividing weight by the square of height. Patients required calorie was calculated using the formula of 25kcal/kg/day. Patient’s feeding started from 30 ml/hr, and then, 30 ml/hr was added to it every three hours to reach the calculated energy within 48-72 hours. For determination of nutritional risk of patients, NUTRIC score form was completed. The clinical history and demographic characteristics of patients were evaluated at the time of admission. The Sequential Organ Failure Assessment (SOFA) score was calculated for all patients in the beginning with the study, day 7, day 14 and Acute Physiology And Chronic Health Evaluation II (APACHE II) score at the beginning and end of study to evaluate the severity and outcomes of disease. In order to measure the serum levels of IL-6, IL-10, TNF-a and hs-CRP, at the beginning and end to the study, 10 ml of vein blood was taken from each patient and after centrifugation and serum separation, serum was kept in -70 ° C until analysis. Serum levels of IL-6, IL-10, hs-CRP, and TNF-a were measured by ELISA kit. The length of ICU stay, duration of ventilator dependency and the 30-day mortality rates were investigated. The sample size was calculated based on the averages comparison formula with α= 0.01 and β= 0.1, µ1= – 0.096، S1= 0.3 ،µ2= – 0.5 ،S2= 0.25 based on the previous study for the serum levels of IL-6 variable (29). The total sample size of 30 patients (15 in each group) was calculated. Based on previous experiences and studies, it was estimated that there would be a 30% dropout after randomization. Thus, the final sample size was considered as 44 patients. The data were analyzed using the statistical software program SPSS 25 (SPSS Inc., Chicago, IL, USA). Data distribution was assessed by Kolmogorov-Smirnov test. Comparisons between groups were made with Independent Samples t-test if data distribution was normal. Comparisons of non-normally distributed samples were performed using Mann-Whitney U test to compare differences between the two groups. Two-sided P < 0.05 was considered statistically significant. Comparisons of qualitative data were done by chi-squar>GET ANSWER