Donepezil

• What is the drug • What is the disease(s) that it treats? • If the drug is now used to treat multiple diseases, highlight the one(s) that was first focused on in the target identification studies which drove the subsequent discovery of a lead compound and drug development. • How is the drug used? • How effective / successful is the drug? • Historical details of when the drug was first approved, its current status. • What is the therapeutic pharmacological target(s) that this drug binds to? • How was this target identified as being promising for the treatment of the disease? • What is the therapeutic pharmacological target(s) that this drug loinds to? • How was this target identified as being promising for the treatment of the disease? • What are the key findings which established the endogenous role of this pharmacological target, and how do these link with the disease?                                        

Sample Solution