Mr. Mohamed Ali is a 55 year old farmer who lives with his wife Amena and 6 children in a 3 room flat in a small village near Mansoura city. His eldest daughter, Wafaa is used to suffer recurrent attacks of acute tonsillitis as a child. When she got married, she was diagnosed with rheumatic heart disease and died during delivery of her first child due to rheumatic heart disease.

His youngest daughter, Hanaa is an 8 year old school girl who missed school today because she could not get up in the morning. She was feeling hot and had difficult painful swallowing. Hanaa mentioned that her best friend Farida had a similar condition 2 days ago. Her mother took her to the doctor who checked her medical records and found that this was the third time that she had this illness within one year.

On physical examination, Hanaa had a temperature of 39 C and appeared acutely ill. She has tonsillitis with intense redness and edema of the mucous membranes, with purulent exudates and enlarged tender cervical lymph nodes.

A throat swab was obtained for culture, which showed Gram positive cocci . Antigen detection test was performed on another throat swab and confirmed group A streptococcal infection. High antistreptolysin O titer (ASO) was estimated in the patient’s serum. Twenty four hours later, cultures on blood agar showed beta hemolysis.

What are the key points in the history?

What are plans of management of this case?

If put drug should be the best drug to be used

 

 

 

Key Points in Hanaa’s history

1. Family Background: Mr. Mohamed Ali lives in a small flat with his wife and six children, indicating a potentially crowded living situation which might contribute to the spread of infections.

2. Previous Health Issues: The eldest daughter, Wafaa, had a history of recurrent tonsillitis as a child, which later progressed to rheumatic heart disease. This family history of rheumatic fever may suggest a genetic or environmental predisposition within the family to streptococcal infections.

3. Current Illness of Hanaa: Hanaa, the youngest daughter, is an 8-year-old who has missed school due to acute illness characterized by:

– Fever (39°C)
– Painful swallowing (odynophagia)
– Intense redness and edema of the tonsils
– Purulent exudates
– Enlarged and tender cervical lymph nodes

4. Epidemiological Link: Hanaa’s best friend, Farida, had a similar condition two days prior, indicating a possible outbreak of streptococcal infection in their community.

5. Recurrent Illness: This is the third episode of similar illness for Hanaa within one year, suggesting a pattern of recurrent tonsillitis, likely due to group A streptococcal infection.

6. Laboratory Findings:

– Throat swab culture shows Gram-positive cocci.
– Antigen detection test confirms group A streptococcal infection.
– High ASO titer indicates recent streptococcal infection.
– Blood agar culture shows beta-hemolysis.

Plans of Management

1. Antibiotic Therapy: Initiate treatment with appropriate antibiotics to eradicate the streptococcal infection. The first-line treatment for confirmed group A streptococcal infection is:

– Drug of Choice: Penicillin V or Amoxicillin for 10 days. If the patient has a penicillin allergy, consider using clindamycin or azithromycin.

2. Symptomatic Treatment: Provide supportive care to alleviate symptoms:

– Analgesics/antipyretics (e.g., acetaminophen or ibuprofen) to reduce fever and throat pain.
– Encourage oral fluids to prevent dehydration.
– Soft diet to ease swallowing difficulties.

3. Monitoring and Follow-up: Schedule follow-up appointments to monitor Hanaa’s progress and ensure that symptoms resolve and treatment is effective. Repeat throat cultures may be necessary if symptoms persist.

4. Prevention of Complications: Educate the family about recognizing signs of rheumatic fever and ensuring timely medical intervention if symptoms arise. Discuss preventive measures such as proper hygiene practices (frequent handwashing, avoiding close contact with infected individuals).

5. Consideration for Tonsillectomy: If Hanaa continues to experience recurrent episodes of strep throat despite appropriate treatment, a referral for an evaluation for a possible tonsillectomy may be warranted.

Conclusion

In summary, the key points in Hanaa’s history highlight a recurrent and significant streptococcal infection, necessitating prompt antibiotic treatment, symptomatic relief, and preventive education for the family. By addressing both the current infection and potential complications, healthcare providers can significantly improve Hanaa’s health outcomes.

 

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