Major milestones

  1. Discuss how findings, from a tissue engineering perspective, will advance medical science.
  2. Comment on how biology and/or physiology are important to the development of the approach/application.
  3. Summarize how the research results found in the literature articles show the potential of the solution and the impact on patient health.
  4. Methods
  5. Describe the critical experimental methods used in the literature articles you cite that are most relevant to understanding this thesis
  6. Describe the critical experimental models used for investigation in the literature articles you cite (in vitro, animal, human, etc.)
  7. Identify all the components/parts of the engineered solution and how they could be produced/obtained
  8. Important Protein Player
  9. Choose a protein that plays an important role in the function of your device/concept
  10. Explain what role the protein plays (ligand, receptor, etc.) and its general structure (alpha helix, beta sheet, multiple units, etc.)
  11. Explain how the protein functions in its role
  12. This protein can be an actual piece of the device, or it can be an endogenous protein that interacts with it.
  13. One Key Signaling Pathway
  14. Describe and diagram one key signaling pathway that is important to the functioning of your device/concept. It is acceptable to copy a diagram of the pathway from a book/drawing, as long as the diagram is cited.
  15. While Sections 5-6 may involve the same protein, describe the protein in Section 5 and the pathway in Section 6.
  16. Alternatively, you can describe a different signaling pathway here that does not involve the protein from Section 5.
  17. The pathway may be something the device directly interacts with, or it may be a pathway involved in the growth/regeneration/repair/genesis of the tissue type that interacts with your device.
  18. Important Cellular Interactions
  19. Describe and diagram one key intercellular interaction that is important to the functioning of your device/concept. It is acceptable to copy a diagram of the interaction from a book/drawing, as long as the diagram is cited

Sample Solution