Musculoskeletal Function
G.J. is a 71-year-old overweight woman who presents to the Family Practice Clinic for the first time complaining of a long history of bilateral knee discomfort that becomes worse when it rains and usually feels better when the weather is warm and dry. “My arthritis hasn’t improved a bit this summer though,” she states. Discomfort in the left knee is greater than in the right knee. She has also suffered from low back pain for many years, but recently it has become worse. She is having difficulty using the stairs in her home. The patient had recently visited a rheumatologist who tried a variety of NSAIDs to help her with pain control. The medications gave her mild relief but also caused significant and intolerable stomach discomfort. Her pain was alleviated with oxycodone. However, when she showed increasing tolerance and began insisting on higher doses of the medication, the physician told her that she may need surgery and that he could not prescribe more oxycodone for her. She is now seeking medical care at the Family Practice Clinic. Her knees started to get significantly more painful after she gained 20 pounds during the past nine months. Her joints are most stiff when she has been sitting or lying for some time and they tend to “loosen up” with activity. The patient has always been worried about osteoporosis because several family members have been diagnosed with the disease. However, nonclinical manifestations of osteoporosis have developed.
Case Study Questions
Define osteoarthritis and explain the differences with osteoarthrosis. List and analyze the risk factors that are presented on the case that contribute to the diagnosis of osteoarthritis.
Specify the main differences between osteoarthritis and rheumatoid arthritis, make sure to include clinical manifestations, major characteristics, joints usually affected and diagnostic methods.
Describe the different treatment alternatives available, including non-pharmacological and pharmacological that you consider are appropriate for this patient and why.
How would you handle the patient concern about osteoporosis? Describe your interventions and education you would provide to her regarding osteoporosis.
Neurological Function:
H.M is a 67-year-old female, who recently retired from being a school teacher for the last 40 years. Her husband died 2 years ago due to complications of a CVA. Past medical history: hypertension controlled with Olmesartan 20 mg by mouth once a day. Family history no contributory. Last annual visits with PCP with normal results. She lives by herself but her children live close to her and usually visit her two or three times a week.
Her daughter start noticing that her mother is having problems focusing when talking to her, she is not keeping things at home as she used to, often is repeating and asking the same question several times and yesterday she has issues remembering her way back home from the grocery store.
Case Study Questions
Name the most common risks factors for Alzheimer’s disease
Name and describe the similarities and the differences between Alzheimer’s disease, Vascular Dementia, Dementia with Lewy bodies, Frontotemporal dementia.
Define and describe explicit and implicit memory.
Describe the diagnosis criteria developed for the Alzheimer’s disease by the National Institute of Aging and the Alzheimer’s Association
What would be the best therapeutic approach on C.J.
Case Study 1: G.J.
Osteoarthritis vs. Osteoarthrosis
- Osteoarthritis (OA): A degenerative joint disease characterized by the breakdown of cartilage, leading to pain, stiffness, and loss of joint function. It is a progressive disease that often affects weight-bearing joints like the knees and hips.
- Osteoarthrosis: An older term that is less specific and may refer to any joint degeneration, including osteoarthritis.
Risk Factors for Osteoarthritis in G.J.
- Age: Older age is a significant risk factor for osteoarthritis.
- Obesity: Excess weight puts additional stress on the joints, particularly the knees and hips.
- Joint Injury: Previous injuries to the knees can increase the risk of osteoarthritis.
- Genetics: A family history of osteoarthritis can increase susceptibility.
Osteoarthritis vs. Rheumatoid Arthritis
Feature | Osteoarthritis | Rheumatoid Arthritis |
---|---|---|
Onset | Gradual | Often rapid |
Joint Involvement | Usually affects a few joints, often asymmetrically | Typically affects multiple joints, often symmetrically |
Morning Stiffness | Mild and short-lived | Severe and prolonged |
Systemic Symptoms | Usually absent | Often present (fatigue, fever, weight loss) |
Diagnostic Tests | X-rays showing joint space narrowing | Blood tests showing rheumatoid factor and anti-CCP antibodies |
Treatment for G.J.'s Osteoarthritis
Non-Pharmacological Treatment:
- Weight Loss: Encouraging weight loss can significantly reduce joint stress.
- Physical Therapy: To improve strength, flexibility, and range of motion.
- Occupational Therapy: To adapt daily activities and promote independence.
- Assistive Devices: Canes, walkers, or braces can help with mobility and pain relief.
Pharmacological Treatment:
- Topical Analgesics: Can provide localized pain relief.
- Oral Analgesics: Over-the-counter pain relievers like acetaminophen or ibuprofen can be used for mild to moderate pain.
- Topical Corticosteroids: Can be injected into the affected joints for short-term relief.
- Hyaluronic Acid Injections: Can provide long-lasting relief by lubricating the joint.
Osteoporosis Prevention
- Diet: Encourage a diet rich in calcium and vitamin D.
- Exercise: Regular weight-bearing exercise can help strengthen bones.
- Medication: If indicated, consider bone-strengthening medications like bisphosphonates or denosumab.
Case Study 2: H.M.
Risk Factors for Alzheimer's Disease
- Age: Advanced age is the primary risk factor.
- Family History: A family history of Alzheimer's disease increases the risk.
- Genetics: Specific genetic mutations, such as APOE4, can increase susceptibility.
Alzheimer's Disease vs. Other Dementias
Feature | Alzheimer's Disease | Vascular Dementia | Dementia with Lewy Bodies | Frontotemporal Dementia |
---|---|---|---|---|
Onset | Gradual | Sudden or stepwise | Gradual | Gradual |
Memory Impairment | Significant memory loss | Variable memory impairment | Significant memory impairment | Early and prominent behavioral changes |
Motor Symptoms | Gait disturbances and balance problems later in the disease | Early motor symptoms, such as gait instability and falls | Early motor symptoms, such as parkinsonism | Early changes in behavior and personality |
Diagnostic Criteria for Alzheimer's Disease
The National Institute on Aging and Alzheimer's Association criteria for Alzheimer's disease include:
- Impairment in memory and learning
- Impairment in one or more cognitive domains
- Functional impairment in daily living activities
Therapeutic Approach for H.M.
The best therapeutic approach for H.M. would involve a multidisciplinary team, including a geriatrician, neurologist, and social worker. The focus should be on:
- Medication: Cholinesterase inhibitors and memantine can help manage cognitive symptoms.
- Non-Pharmacological Interventions: Regular physical activity, cognitive stimulation, and social engagement can help slow cognitive decline.
- Supportive Care: Addressing behavioral symptoms, providing assistance with activities of daily living, and ensuring safety.
- Family Support: Educating and supporting family members to help them cope with the challenges of caring for a loved one with dementia.
By addressing the underlying causes of cognitive decline and providing appropriate support, it may be possible to slow the progression of the disease and improve the quality of life for individuals with Alzheimer's disease.