Pathogenicity

Consider what makes your pathogen pathogenic! o What are the key virulence factors? o Are there typical “risk factors” associated with infections with this pathogen? For example, some pathogens target mainly children, some target immunosuppressed individuals. o What type(s) of infections does the pathogen cause? Are the infections associated with a particular body location or system? o Does it cause opportunistic infections? o What are the outcomes of infection? What makes this pathogen a health problem? o What are the typical host responses to your pathogen? ie) does it cause inflammation? Immunosuppression? Septic shock? Are there long-term consequences (sequelae) for survivors? Antibiotic and disinfectant resistance and susceptibility o What is known about the range of antibiotic/antiviral drug or disinfectant resistance of this pathogen? o What types of antimicrobial agents are effective against this pathogen? o Are specific sterilization and disinfection routines in place for dealing with this pathogen in healthcare settings