Psychopharmacology

  Precursor substance: Tyrosine     1. Search for a diagram showing how the various enzymes convert this substance to a. Serotonin (Diagram 1) b. Dopamine (Diagram 2) c. Norepinephrine. (Diagram 3) Paste the diagram or add the link 2. Identify and briefly describe each chemical step required to create each neurotransmitter (Six paragraphs) a. Diagram 1 (Two paragraphs) b. Diagram 2 (Two paragraphs) c. Diagram 3 (Two paragraphs)
Diagram 2: The conversion from Tyrosine to dopamine also follows a three step process beginning with Tyrosine hydroxylase converting Tyrosine into L-DOPA and then followed by another enzymatic action, this time by aromatic amino acid decarboxylase which converts L-DOPA in dopamine. Diagram 3: Similar to diagrams 1 and 2, Norepinephrine also requires a three step process for its formation; beginning with an enzymatic action from Tyrosine hydroxylase converting Tyrosine into Dihydroxyphenylealanin (L-Dopa), followed by another enzymatic action from Aromatic Amino Acid Decarboxylase converting L-dopa into Dopamine, and finally Monoamine Oxidase catalyzing the reaction between Dopamine and Oxygen molecules which forms Norepinephrine

Sample Solution

Diagram 1: The conversion of tyrosine to serotonin begins with the enzyme tyrosine hydroxylase catalyzing the reaction that converts tyrosine into L-DOPA. Aromatic amino acid decarboxylase then catalyzes the conversion of L-DOPA into Dopamine. Finally, an additional enzyme monoamine oxidase acts on dopamine to form serotonin.