Research in molecular biology and genetics
Something on the order of one third of us will have cancer at some point in our lives.
Even if you escape, someone close to you will have cancer. The good news is that
many of us will survive the encounter, though many will not. Diagnosis and treatment
are advancing at a great rate, and many of these advances are coming from
research in molecular biology and genetics. For this writing assignment, pick a
cancer, any cancer, and address the following for that cancer:
1. Introduce the subject in terms your mother would understand (assuming
she’s not a molecular geneticist or oncologist). Tell us about symptoms,
age-of-onset, frequency, risk factors, etc. Are there predispositions for
getting this cancer?
2. Please provide more molecular details after the introduction. Describe in
detail what is known about the cancer including genes that have been
identified with this cancer. Please make sure to include mutations. If a
cancer has more than one gene associated with, pick only one gene.
Please make sure you discuss mutations and how these mutations
change the protein. In other words, what was the proteins normal function
and how does the mutation change this. Use the “Hallmarks of Cancer”
wheel that was discussed in the PowerPoint lecture to help classify the
protein(s). Is this cancer genetic (inherited) or not?
3. Finally, conclude with ongoing research, potential treatments, and if any
clinical trials are taking place.