How far do you agree that the Battle of Cable Street in 1936 was a major victory for anti-fascism in the UK?
reported that CQ is the most common antimalarial sold across the counter with high frequency of prescription in public as well as private health facilities as compared to other antimalarials (Mishra et at. 2011) As we employed dried blood spot method for sample collection, it was not possible to detect any artemisinin compounds. Also, short half-life of artemsinin requires sophisticated techniques as well as plasma sample collection. However, the presence of residual artemisinin cannot be ruled out as high prescription rate of this antimalarial has been previously observed in the country (Mishra et at., 2011). Both MQ and QN are not recommended for uncomplicated malaria, but their residual levels were still found to be present in the patients, although in very few samples and that too at low concentrations. By detecting the presence of residual anti-malarial levels on day 0, it can concluded that this be due to; (1) Self-medication due to non-availability of reachable drug to the dispensing facility or the practitioner leading to inadequate dosing and there by inability to control infection(Hodel et al. 2009; Hodel et al. 2010; Jombo et al. 2011; Nsimaba et al. 2005; Souares et al. 2009), (2) Irrational treatment practices by the physician at the study sites with high transmission intensity of malaria parasites, where all febrile patients were treated with a variety of available antimalarial drugs(Aborah et al. 2013 and Khan et al. 2012), (3) Unawareness regarding the suitable antimalarial drug to be used for treating malaria (4) Treatment of previous episode of infection with antimalarial drug after then re-infection with a new parasite resulting of previously consumed episode of drug as residue in blood (Quashie et al. 2005; Stepniewska and White 2008 ). These factors contribute to increased drug pressure on the parasite thus encouraging resistance in Plasmodium species (Jamison et al. 2006). With these observations, it can be deduced that the entry criteria based on self reporting of previous drug intake or information collected in case record forms are not reliable at least in this population. Assuming that the patients with residual SDX in their whole blood had taken a single dose of SP according to body weight, most patients must have taken the drug, 1 month (median 29 days) prior blood withdrawal. Furthermore, it is also possible that patients might have taken a sub-therapeutic dose of SP more recently. Detection of a drug with very trace and long duration does not allow to determination of whether a patient had monotherapy or as part of an ACT or complete dose had been taken. The influence of age and sex on the probability of residual antimalarials at entry showed no significant relationship in our study indicating uniform antimalarial prescription or intake behaviour in the popula>GET ANSWER