two genetic diseases with Mendelian transmission
Objective: To research two genetic diseases with Mendelian transmission, develop two pedigrees, and highlight the different inheritance patterns-
Part I: Choose one Autosomal Dominant disease and one Autosomal Recessive disease
1- Research the two diseases that you chose so you understand:
a- pattern of transmission
b- the characteristics of the disease
Part II: Develop an inheritance chart
1- Create a fictitious family for each of the diseases you have researched
a- draw a pedigree diagram for the family that highlights inheritance patterns for the
disease- There must be at least 4 affected family members in the pedigree-
b- Remember, the purpose of the assignment is to learn about inheritance patterns-
c- Examples of pedigrees can be found in D2L, in your text book, or online by searching “pedigree charts” in Google-
d-The chart should be completed in a format that can be submit via D2L-
2- Develop a legend that explains the symbols that you use in your diagram- The legend should include
a- Boxes = males, circles = females
b- Shade/color in boxes to indicate a particular trait or chronic illness-
c- Include each color in the legend to indicate what it represents
d- Relationships:
i- A vertical line connects the spouse or mate of a male or female
ii- A vertical line indicates children
iii- Indicate deceased members of the family
iv- Place a star over the person who is the focus of the chart (proband)
Part III: Genotype each family member
1- State the genotype of each family member either in a chart or in the individual's symbol in
2- Use a Punnett Square if necessary.
Part IV: Phenotype
1- Using complete sentences in paragraph forrn, describe the phenotype for each of the
diseases-
Part V: Chance for next generation
1- What are the chances that offspring in the next generation will be affected by the disease?
58.
home work basic math
1- Evaluate: 5 + 23.7 + 8.7 + 9-85 (please see section 0.4 for further review)
2- Evaluate: 7-83 - 52 (please see section 0.4 for further review)
3- Multiply: 4-56 *3 (Please see section 0.4 for further review)
4- Write the decimal equivalent of: (please see section 0.4 for further review)
5- Find the prime factorization of: 360 (Please see section 0.2 for further review of prime numbers)
6- Simplify: (please see section 0.2 for further review)
7- Simplify: (please see section 0.2 for further review)
8- Simplify: (please see section 0.3 for further review)
9- What is 24% of 112?2 (please see section 0.5 for further review)
10- Simplify: (please see section 0.3 for further review)