Properties of the anterior pituitary hormones with the posterior pituitary hormones.

• • Wide-ranging depending on the specific hormone affected.
  • Can include growth disorders, infertility, hypothyroidism, adrenal insufficiency, and metabolic disturbances.

Posterior Pituitary Hormones

• Regulation:

  • Controlled by neuronal signals from the hypothalamus.  
  • Neurons synthesize hormones in the hypothalamus and transport them to the posterior pituitary for storage and release.  

• Mechanism of Secretion:

  • Neural tissue.
  • Stores and releases hormones produced by the hypothalamus.  
  • Hormone release is triggered by nerve impulses.

• Vulnerability to Brain Trauma and Inflammation:

  • Highly susceptible to damage from brain trauma and inflammation.  
  • Can disrupt neuronal pathways, affecting hormone synthesis, transport, and release.

• Long-term Consequences of Dysfunction:

  • Can lead to diabetes insipidus (insufficient ADH production), impaired water balance, and problems with childbirth (insufficient oxytocin).

Key Differences

• Regulation: Anterior pituitary is primarily regulated by hormones, while the posterior pituitary is regulated by neuronal signals.  
• Mechanism of Secretion: Anterior pituitary produces its own hormones, while the posterior pituitary stores and releases hormones produced elsewhere.
• Vulnerability: Posterior pituitary is generally more vulnerable to brain trauma and inflammation due to its neural nature.

Similarities

• Both play crucial roles in various physiological processes.  
• Both are influenced by the hypothalamus.  
• Dysfunction in either can have significant and long-lasting health consequences.

This is for informational purposes only. For medical advice or diagnosis, consult a professional.

Anterior Pituitary Hormones

• Regulation:

  • Controlled by hypothalamic hormones released into the hypophyseal portal system.  
  • Releasing hormones stimulate hormone production, while inhibiting hormones suppress it.  
  • Negative feedback loops involving target organ hormones regulate secretion.  

• Mechanism of Secretion:

  • Glandular tissue.  
  • Produces and releases its own hormones.  
  • Hormone synthesis and release are regulated by hypothalamic hormones.  

• Vulnerability to Brain Trauma and Inflammation:

  • Can be affected by disruptions to the hypothalamic-pituitary axis caused by brain trauma or inflammation.  
  • This can lead to hormone deficiencies or excesses.  

• Long-term Consequences of Dysfunction: